Dorothy Sears is an expert in systems biology, metabolism, diabetes and prevention science.

Sears is a is professor of nutrition in the College of Health Solutions and a member of the school's research council, review board and mentorship program.

Professor Sears' research focuses on dietary and behavioral intervention, systems biology, metabolomics, gut microbiome, epigenetics, gene expression profiling, and single gene analyses in humans and rodent models.

Sears has collaborated with the National Institute of Health and American Heart Association and other international organizations. She is lead investigator of multiple clinical studies of the metabolic and vascular effects of prolonged sitting funded by the National Institutes of Health and the American Heart Association.